|AP/MALDI (ng) HR Ion Source|
|Monday, 01 June 2015 00:00|
What is AP-MALDI?
The AP-MALDI (Atmospheric Pressure, Matrix Assisted Laser Desorption/Ionization) source has been our signature product since the inception of the company. Currently in its’ fifth generation -called AP-MALDI (ng) HR - our AP-MALDI ion source uses several key pieces of technology MassTech has developed over years of work with this product. Furthermore, as the AP-MALDI operates at atmospheric pressure (requiring zero pumping time after installation) samples are not required to be vacuum compatible. This gives you the ability to use volatile or semi-volatile solvents and matrices in your sample, allowing for new and non-traditional MALDI applications.
The AP-MALDI source is compatible with Mass Spectrometers from all major Mass Spectrometer manufacturers. Due to the atmospheric pressure interface, you can switch from ESI to AP-MALDI in minutes, if not seconds! For labs with occasional MALDI needs, or for labs without a dedicated MALDI Mass Spectrometer, the AP-MALDI source is the perfect solution.
At MassTech, we have developed applications using the AP-MALDI in conjunction with instruments with MS/MS capabilities, such as our own MT Explorer 50, allowing us to do MALDI MS/MS and do work such as detection and even identification of bacteria and other biological samples. If your instrument has accurate mass measurement capability, with the AP-MALDI you can do accurate mass MALDI. As a result, we have seen excellent results with instruments such as the Thermo QExactive Orbitrap and the latest Agilent 6000 series.